Automated NGS Library Preparation Complex workflows. Clear solutions. Automated with precision.
- Automation brings structure and reliability to complex, multi-step workflows
- Improved consistency in library preparation helps reduce low-quality NGS reads
- Smart resource management and efficient use of consumables
- Flexible system configuration tailored to your protocols and specific workflow needs
- Scalable solutions that grow with your requirements
Analytik Jena enables users to begin automating their NGS library preparation at the level that best fits their current needs – from targeted entry points to fully automated workflows. With a modular system design, solutions can be easily expanded and adapted as processes evolve. This ensures a future-proof investment. Tailored configurations allow seamless integration into existing workflows.
NGS Library Preparation – Modular, Scalable, Reliable
NGS library preparation involves a series of precisely coordinated steps – from fragmentation and end-repair to adapter ligation, PCR enrichment, and quality control. Each of these steps demands the highest level of accuracy and reproducibility to generate high-quality sequencing data. Automation with the CyBio FeliX from Analytik Jena delivers not only technical precision but also maximum flexibility. Users can automate specific process steps with a single device, combine two systems to increase the level of automation, or integrate the entire workflow into a robotic platform. The result is a solution that adapts perfectly to the needs of the lab – today and in the future.
- Modular design – Start with targeted automation of individual library prep steps and scale up to full workflow automation
- Upgradeable – Systems can be easily expanded as requirements grow
- Compact footprint – High performance in a space-saving format, ideal for any lab environment
- Robust technology – Precise liquid handling for critical steps
- Customizable workflows – Flexible configuration tailored to specific protocols and lab needs
- Versatile applications – Suitable for other molecular biology tasks such as DNA/RNA extraction, qPCR setup, or assay development
Brochures
| Title | Language | Info |
|---|---|---|
| Br CyBio Lab Automation Solutions (EN) | en | PDF, 5 MB |
| Automated NGS Library Preparation (EN) | en | PDF, 2 MB |
| Produktübersicht Life Science, Liquid Handling & Automation (DE) | de | PDF, 7 MB |
| Product Overview Life Science, Liquid Handling & Automation (EN) | en | PDF, 7 MB |
CyBio FeliX – Key Component for Automated NGS Library Preparation
When every step matters, you need systems that think ahead. Analytik Jena’s preconfigured automation solutions offer optimal setups for NGS library preparation – flexible, scalable, and ready to use. Built around the versatile liquid handling system CyBio FeliX, all critical steps can be reliably automated:
- Extraction and Fragmentation
- cDNA synthesis and End repair
- Adapter ligation and Indexing
- Amplification and Clean-up
- Size selection and Pooling
Whether you’re automating individual process steps or implementing fully integrated workflows – our systems grow with your needs and deliver maximum efficiency, reproducibility, and walk-away time.
- Economical Level Automation Individual CyBio FeliX configurations for dedicated process steps such as extraction, normalization, library preparation, or pooling & dilution – ideal for modular entry into automation.
- Intermediate Level Automation Combination of multiple CyBio FeliX systems to increase the degree of automation and extend walk-away time
- Advanced Level Automation Fully automated workflows with robotic integration, lidding/de-lidding, barcode and fluorescence readers, as well as integrated thermocyclers for PCR and qPCR
Our preconfigured systems are compatible with all common standard kits and protocols. Predefined methods and scripts can be easily customized and implemented – ensuring a smooth start and maximum efficiency.
All essential functional modules are already thoughtfully included, as are advanced integration options for fully automated workflows:
- On-deck modules: Magnetic adapter, heating/shaking modules, gripper
- Extensions: Integration of thermocyclers for PCR and qPCR, automated cooling, storage, and readers
- Robotic arm: For automated transfer of labware and reagents
System control – from a single CyBio FeliX to fully automated workflows – is managed via a powerful and unified software solution: CyBio Composer, combined with the user-friendly CyBio AppStudio.
- Centralized control of all components via CyBio Composer
- Pre-configured methods and scripts for fast implementation
- Easy customization for individual protocols and workflows
With CyBio FeliX automation concepts, laboratories invest in a future-proof solution that grows with their needs. The systems are fully expandable and can be individually configured – ensuring maximum flexibility and efficiency in NGS library preparation.
Products
Advanced Level Automation - End-to-End NGS Library Preparation
Two different configurations for fully automated NGS library prep with integrated CyBio FeliX Liaquid Handler. From extraction to pooling, all steps are seamlessly connected, maximizing throughput, consistency, and contamination control.
Order number: LHA-NGS-ALOA
Economical Level Automation - Single CyBio FeliX Configurations
Streamline NGS library prep with up to four stand-alone CyBio FeliX deck setups, each tailored for dedicated tasks (Extraction & CleanUp, Normalization, Library Prep, Dilution & Pooling) to boost efficiency, flexibility, and precision in your workflow.
Order number: LHA-NGS-ELOA
Intermediate Level Automation - Dual CyBio FeliX Automation
Two pre-configured CyBio FeliX units connected via robotic arm enable seamless automation of multiple NGS library prep steps, with spatial separation of pre- and post-PCR workflows for enhanced process integrity.
Order number: LHA-NGS-ILOA
Order Information
Order number |
Description |
|---|---|
| LHA-NGS-ALOA | Advanced Level Automation - End-to-End NGS Library Preparation |
| LHA-NGS-ELOA | Economical Level Automation - Single CyBio FeliX Configurations |
| LHA-NGS-ILOA | Intermediate Level Automation - Dual CyBio FeliX Automation |
Software
CyBio Composer
As the backbone of our automation and liquid handling software, CyBio Composer ensures the reliable and detailed operation of Analytik Jena instruments as well as accessories and devices from 3rd party suppliers facilitating detailed control on a scripting level. While mostly working in the background, CyBio Composer monitors user permissions and records user interactions, errors and other execution information.
- Powerful scripting environment
- Direct access to all hardware functions and liquid handling parameters
- Possibility of connecting to databases and LIMS systems
- Spporting > 150 drivers
| Product | Required | Included |
|---|---|---|
| Economical Level Automation - Single CyBio FeliX Configurations (LHA-NGS-ELOA) | ||
| Intermediate Level Automation - Dual CyBio FeliX Automation (LHA-NGS-ILOA) |
Downloads
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