PQ LC Series Highly Sensitive Solutions for the Determination of Element Species

  • Highly sensitive – lowest detection limits
  • Powerful: simultaneous determination of major species and ultratraces
  • Efficient: short analysis times and intuitive operation

LC-ICP-MS is versatile, robust and highly sensitive methods for the determination of element species in various fields. The coupling of the PlasmaQuant MS instruments and the systems of the PQ LC series offers outstanding precision and accuracy in element speciation, with well defined and clearly separated peaks. The combination of excellent chromatography and the high sensitivity of PlasmaQuant MS enables detection limits for arsenic or chromium species in the sub-ppt range (<1 ng/l).

Element Speciation Using HPLC Coupling

PQ LC is a series of modular chromatography systems for the separation of element species using high-performance liquid chromatography (HPLC). The PQ LC series is available as a compact routine LC system for limited laboratory space or as a fully equipped LC model with various upgrade options such as temperature control for the sample injector, column oven or UV/Vis detector.

  • Simultaneous identification of major and trace species thanks to outstanding sensitivity and a wide linear operation range of the PlasmaQuant MS
  • High sample throughput and minimum downtime thanks to short warm-up and analysis times, flexible automation and connection of upgrade modules, as well as low maintenance requirements
  • Simple handling and smooth workflows thanks to intuitive handling, fast change of applications, interactive and user-friendly software interface, as well as automatic safety check
  • Flexible configuration and individual adaptation to your needs thanks to various upgrade modules, and flexible automation with variable vial racks and adaptors for microtiter plates

It is a very flexible system to fit for purpose by pick and mix what you really need.

PQ LC Series for High Performance Liquid Chromatography

The combination of PQ LC and PlasmaQuant MS (LC-ICP-MS) offers a versatile, robust, and highly sensitive solution for the determination of element species in various kinds of samples. The species or chemical form of elements determines their mobility, bioavailability, and toxicity. Since characteristics vary dramatically depending on the species in which an element is present, careful characterization of environmental, food, and agricultural samples and of consumer goods is required. Liquid chromatography or ion chromatography makes it possible to separate these species. The subsequent detection by inductively coupled plasma mass spectrometry provides a highly sensitive method for their quantification. Hence, LC-ICP-MS provide an essential tool for assessing benefits and/or risk of elements present in the sample.

Environmental – elemental speciation plays an important role in respect to evaluating chemistry, geochemistry or bio-geo-chemistry of different pollutants as well as their bioavailability and toxicity towards organisms or their chemical and physical effects on natural cycles. Elements of interest in species identification are arsenic, selenium, chromium, mercury, cadmium, and many more.

Food and Agriculture – the quantification of major and trace elements, and of essential, nutritional, and potentially toxic elements is a common application in ICP-MS. Since an element can be essential or toxic just based on the oxidation state or compound in which it occurs, the determination of elemental species in foods and beverages is crucial for ensuring the safety of foodstuffs. LC-ICP-MS makes the determination of elemental species possible, for example in the analysis of food samples, such as sea fish, rice, chocolate, and apple juice for arsenic, selenium, or chromium.

Clinical and Pharma – multiple regulations and standards describe quality control procedures to ensure the efficiency and harmlessness of pharmaceutical products . During production, pharmaceutical products may, for example, be contaminated with chromium. Therefore, the potential toxicity must be evaluated by identifying the species present according to defined standards. In clinical analysis, element speciation plays a minor role. However, the identification of arsenic species in body fluids, such as whole blood, serum, or urine, gives insight for the risk assessment of workplaces.

Products

PQ LC - HPLC System, non metal, PEEK

Metalfree LC system with PEEK, for low backgrounds on target isotopes in speciationanalysis

Order number: 810-88409-0

PQ LC - HPLC System, stainless steel

Fully equipped LC system, with various upgrade options, such as temperature control for the sample injector, column oven or UV/Vis detector

Order number: 810-88403-0

Order Information

Order number

Description

810-88409-0 PQ LC PQ LC - HPLC System, non metal, PEEK
810-88403-0 PQ LC - PQ LC - HPLC System, stainless steel

Accessories

Eluent Tray for PQ LC - incl. 4 bottles

Order number: 810-88413-0

PQ LC Sample Injection System - non-metal, PEEK

Order number: 810-88415-0

Trigger Box Relay for control of external accessories (e.g. Laser Ablation, HPLC)

Order number: 810-88061-0

Software

Data Apex Clarity

advanced Chromatography Data Station (CDS) with wide range of data acquisition interfaces (A/D converters, LAN, USB, RS232) allows connection to many GC or LC chromatograph from several suppliers, with optional control over modules for data acquisition, processing and instrument control.

Product Required Included
PQ LC - HPLC System, non metal, PEEK (810-88409-0)

Data Apex - Clarity Chromatographie Station

advanced Chromatography Data Station (CDS) with wide range of data acquisition interfaces (A/D converters, LAN, USB, RS232) allows connection to many GC or LC chromatograph from several suppliers, with optional control over modules for data acquisition, processing and instrument control.

Product Required Included
PQ LC - HPLC System, stainless steel (810-88403-0)

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