Drug discovery
- Flexible solutions adapting to your workflow
- Method development support
- Scalable liquid handling and automation systems
- Precise thermocycling technology with reproducible results
flexibility you need, data you can trust Compact solutions optimized for high throughput screening and assay development
In pharmaceutical research, adapting as you go along is the key to success. Our compact and scalable solutions integrate seamlessly into your workflows and are tailored to your specific application with our expert method development. The result: reproducible data that empower faster, more confident decisions to nominate the right candidates for your next breakthrough.
Solutions
Highlights
- Automation under your laminar flow hood
- Parallel pipetting in 96, 384 and 1536 well-plate format
- Automated end-point thermal cycling in 96 and 384 well-plate format for NGS sample preparation
Applications
- Cell-based assays
- High throughput screening
- Automation for drug discovery workflows
- Gene expression and gene editing
- Thermal protein and interaction analysis
- Dissolution studies
Customer voices
Easy to use, fast, the multiplexing works great, the curves are beautiful
“We tested the qTOWER iris in our lab. The device is easy to use, fast, the multiplexing works great, the curves are beautiful. And the print report is the icing on the cake. A bonus is the gain settings to enhance the signal depending on the dye. This saves us money in assay development, as well as the freedom to choose the plastic. Iris makes our work easier in every respect - and it's super quiet too.“
Maja Studencka-Turski, Scientific Lead, myPOLS Biotec, Konstanz
Extremely precise, robust, and reliable
“The SPECORD PLUS photometer has proven extremely precise, robust, and reliable. With its 2x 8-cell changer, it's ideal for double UV online dissolution systems.”
Thomas Pfammatter, CEO, SOTAX AG
Indispensable for our workflow
“The CyBio FeliX proved to be indispensable for our workflow. Particularly important for us was the fine-grained control of liquid dispensing for gentle compound additions to minimize cell disturbance.“
Dr. Ralf Schwandner, CEO & Founder, Assay.Works GmbH
CyBio FeliX was the best choice for our application.
“We have tested several liquid-handling platforms. CyBio FeliX was the best choice for our application.”
Dr. Maria Barthmes, Product Manager Nanion Technologies
Challenging liquid handling tasks easy to achieve
“We at Ionovation use the CyBio FeliX for two unusual applications: as a media supply for an organ-on-chip system and for an lipid bilayer electrophysiology workstation. The flexibility and the programming options of the CyBio FeliX make both of these challenging liquid handling tasks easy to achieve.“
Dr. Roland Hemmler, Product Manager Ionovation GmbH
E-book: sample preparation for next generation sequencing
Our e-book “Sample Preparation for Next-Generation Sequencing” offers selected applications of our products regarding the manual library construction and the partial automation of library preparation. Get all the necessary information for your sequencing challenges.
Applications
Cell-based assays
Studies on cell viability and cytotoxicity provide valuable insights into the effects of substances on living cells. For assay setup, our modular workstation CyBio FeliX is a compact device with an unmatched size-performance ratio including liquid handling adapters, grippers and magnets. Discover automation under your laminar flow hood for reproducible and efficient cell viability and cytotoxicity assays and more.
Application notes
Metabolic viability assay: RealTime-Glo
Multiplexed cell viability & cytotoxicity assays: RealTime-Glo, CellTox Green
High-throughput screening
Efficient and precise sample preparation is essential for reproducible results in MALDI-TOF mass spectrometry – especially in early-stage drug discovery. Our liquid handling systems enable automated workflows for matrix addition, co-crystallization, and spot deposition with highest accuracy and minimal sample consumption. TheCyBio Well vario allows for parallel and reliable pipetting – ideal for robust and standardized MALDI-TOF-MS workflows.In addition, our flexible systems also support other sample preparation workflows for high-throughput screening – whether you're working in 96-, 384-, or 1536-well plate formats.
Brochure HTS MALDI sample preparation
Website MALDI sample preparation
Thermal protein and interaction analysis
Thermal protein and interaction analyses reveal key insights into biomolecular stability and binding. Our solutions deliver high-throughput capacity and automation for these applications. Our qPCR devices of the qTOWER iris series cover a unique UVA–NIR spectral range, offering the freedom to choose any dye.
Application notes
Application Note – Protein stability analysis with SYPRO® Orange
Technical Note – β-Lactoglobulin thermal shift assay with CPM on qTOWER iris
Gene expression
Gene expression workflows rely on precise thermal cycling — from reverse transcription to downstream quantification. Our Biometra thermal cyclers deliver reliable PCR performance for essential steps such as cDNA synthesis and amplification. For quantitative expression analysis, the qTOWER iris series supports sensitive and multiplexed qPCR in 96- and 384-well formats. Both platforms can be integrated into automated workflows — with TRobot II and qTOWER auto enabling high-throughput real-time and endpoint PCR applications. For labs also working on gene editing, our systems support essential steps such as construct generation or CRISPR plasmid preparation, enabling consistent and high-quality results across gene editing protocols.
Application notes
Multiplex detection of six targets in one qPCR run using the qTOWER iris
Performing six-color probe-based qPCR without crosstalk or calibration
Dissolution studies
To determine the dissolution characteristics of pharmaceuticals inside the human body and monitor substance concentrations over time, molecular spectroscopy is an ideal method: simple, easy to use and automated. Our UV/Vis photometers of the SPECORD PLUS series measure up to 14 samples in one batch and deliver excellent measurement stability.
Application support
An entire team to keep your research up and running: Our in-house specialists support you in the development of new methods and protocol scripts for liquid handling and automation solutions, while our application specialists will make sure that you get the most out of our solutions, providing applicative-methodological trainings and application support.
And our technical specialists will be on your site for regular servicing or in case of service incidents.
Software solutions
With our powerful and scalable software packages, you can control our analysers, liquid handling and thermocycling products up to complex automation systems. Different user levels in the liquid handling area allow you to adjust settings and data processing, customise workflows and adapt them to different user levels.
Products and solutions
CyBio Well vario series
- Parallel pipetting in 96-, 384- and unique 1536-well format
- Fully integrable
- Precise down to 200 nL
CyBio FeliX series
- Unmatched footprint-to-functionality ratio
- Interchangeable pipetting heads
- Modular, scalable and integrable
qTOWER iris series
- Unique UVA - NIR spectral range
- Free choice of dyes, labware, and reagents
- Ergonomic and whisper-quiet
Biometra TRobot II series
- Automated solution in 96- and 384-well format
- Fully integrable, compact and whisper-quiet
SPECORD PLUS series
- Long-term stability of measurements
- Automated measurement of up to 14 samples in one batch
- Full control via LMS possible
- FDA 21 CFR Part 11 compliance module
qTOWER³ auto series
- Automation-ready
- Compact design with external power module
- Scalable throughput with up to 4 devices in one automated system
Biometra thermal cycler series
- Thermocycler-Management-Software for GMP-compliant lab work
- Exceptional ramping rates & temperature homogeneity over the entire block
CyBio automation
- Preconfigured & customizable systems
- Seamless third-party solution integration
- Tailored hard- & software development
Downloads
AppNote: Modularly automated preparation of NGS libraries
Open PDF
Automated RealTime-Glo™ MT Cell Viability Assay Multiplexed with CellTox™ Green Cytotoxicity Assay
Open PDF
Br MALDI Sample Preparation (EN)
Open PDF
Detecting Protein Melting Temperatures via Thermal Shift Assay with SYPRO® Orange Dye (EN)
Open PDF
Enabling 6-Target Multiplex Real-Time PCR on qTOWER iris (EN)
Open PDF
Performing a Six-Color Probe-based Assay Without Signal Crosstalk and Calibration Effort (EN)
Open PDF
Contact
The newsletter of Analytik Jena frequently keeps you posted about:
- News
- Trends and developments
- Events