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Achieving Ultra-Sensitive Inductively Coupled Plasma – Mass Spectrometry (LA-ICP-MS) Analysis with the J200 LA Instrument: A Glass Sample Study Application Note · PlasmaQuant MS Elite

Challenge

  • Determination of the absolute mass in solid samples and detection limits using on a glass sample study.

Solution

  • High-precision analysis of solid samples with superior sensitivity (down to ppb levels) and little to no sample preparation using LIBS and LA-ICP-MS.

Introduction

Laser ablation (LA) is a direct solid sampling technique that uses a laser pulse to remove small amounts of mass (pg – fg scale) from a sample of interest. Combining LA with inductively coupled plasma – mass spectrometry (ICP-MS) offers very attractive technical benefits for the analysis of solid samples, which include little to no sample preparation, high precision measurements, and superior sensitivity (down to ppb levels) with respect to other atomic spectroscopy methods. LAICP-MS analysis also offers both elemental and isotopic information. Depending on the laser sampling method deployed, LA-ICP-MS can be used for traditional bulk analysis, as well as for spatially-resolved analysis such as elemental/isotopic mapping and depth profiling.

The following application describes the analysis of glass samples (NIST SRM, trace elements in glass) to determine the absolute mass that can be detected and the limits of detection (LODs) when interfacing an Analytik Jena PlasmaQuant®  MS Elite ICP-MS and Applied Spectra Inc.’s J200 LA instrument.

Download the complete Application Note

Elemental Mapping of Printed Ink Using the J200 Tandem LA-LIBS Instrument in Combination with the PlasmaQuant® MS Elite ICP-MS (EN)

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PlasmaQuant MS Series Robust system for efficient, stable characterization of high matrix samples: PlasmaQuant MS offers excellent plasma robustness for high matrices, minimized drift at changing matrix load and efficient interference management with outstanding ease of use.

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