multi N/C 4300 Series The Trace Detector

  • Optimum sensitivity at TOC trace levels
  • Short measuring times and highest oxidation power due to high-energy UV radiation at 2 wavelengths
  • Economical operation thanks to long-lasting components and inexpensive reagents
  • Time-saving automation functions for the ultrapure water range
  • New intuitive software with live result display

An extremely sensitive and precise UV digestion device, which is ideally suited for ultra-pure water analysis - in the trace range even without persulfate.

TOC trace analysis without oxidizing agents

The highly precise multi N/C 4300 UV is specifically designed for TOC analysis at the ultra-trace level. He is ideal for analyzing boiler feed water in large-scale power plants, water for injection purposes and TOC cleaning validation in the pharmaceutical sector. Equipped with a high-performance UV reactor, all carbon compounds can be digested rapidly and completely, even in difficult matrices such as monitoring of electrolysis baths for electroplating. At the ultra-trace level, the UV reactor enables digestion without persulfate, which makes operation more efficient, avoiding TOC blank interferences. The device can be retrofitted with a solids module for non-catalytic high-temperature combustion.

  • TOC analysis at the ultra-trace level thanks to maximum injection volumes of up to 20 mL
  • Persulfate-free sample digestion thanks to high-power long-life UV reactor
  • High NPOC sample throughput due to parallel purging and measurement
  • New intuitive software with live result display and 21 CFR Part 11 compliant pharma module
  • Significant time savings thanks to long-term stable calibrations
  • Automatic acidification, purging and sample homogenization
  • Device can be upgraded for TOC analysis of solids by means of non-catalytic high-temperature combustion
  • Five-year warranty for the focus radiation NDIR detector and three-year warranty for the UV reactor

Download Product Information

High performance for wet chemical UV digestion

TOC analysis at the ultra-trace level requires precision and efficiency. Flow injection from the syringe pump combined with the focus radiation NDIR detector enables a low detection limit of 1 µg/L C at the ultra-trace level.

Sample digestion is performed using a long-life high-power UV reactor with two oxidation wavelengths. The particularly high-energy UV radiation at 254 nm and 185 nm oxidizes even extremely stable carbon compounds quickly and completely, and this without any oxidizing agents such as persulfate. Not only does this make operation safer and more economical, it also delivers more accurate results as it avoids distortion of measurement results due to reagent blank values.

The highly sensitive FR NDIR detector, combined with the high radiation intensity of the UV reactor, makes for precise CO2 detection at the trace and ultra-trace level and also makes the device suitable for aggressive matrices.

The Easy Cal function enables stable long-term multi-point calibration from a single stock solution, saving time and effort.

The automation solutions are specifically designed for applications at the ultra-trace level, making sample preparation and analysis more efficient, and they can be tailored to the needs of our customers. Our comprehensive autosampler portfolio enables automatic acidification, parallel purging and magnetic stirring to homogenize samples, as well as external needle rinsing to prevent sample carryover. The EPA sampler allows operation with polymer septa for TOC analysis in ultrapure water. Optimum blank value minimization is achieved by permanent purging of reagents.

TOC solids measurement can be configured using the additional module HT 1300, which offers manual sample introduction via ceramic boats. This is used for non-catalytic high-temperature combustion at up to 1800 °C (with additives) in a ceramic combustion tube.

Manual TIC analysis for solids by direct acid digestion is available with the TIC module.


Product Variants at a Glance

multi N/C 4300 UV

Extremely sensitive TOC analyzer, which is ideally suited for ultrapure water analysis, especially in pharmaceutical applications. High-power UV oxidation also makes it an ideal device for TOC analysis in complicated matrices, where combustion devices reach their limits.

Solids analysis (optional):

  • Non-catalytic high-temperature combustion with HT 1300
  • Acid digestion module for TIC analysis in solids

No nitrogen analysis



  • Ultrapure water analysis (water for injection - WFI) in pharma industry
  • TOC cleaning validation by swab extraction or final rinse method
  • Analysis of boiler feed water and condensates in power plants
  • Drinking water analysis
  • Highly saline or acidic samples such as in electroplating




Show applications


Food & Agriculture

Show applications


Technical Data


Injection Volume

Limit of Detection

Gas supply

Digestion Mode

Optional Parameters



Measuring Time

Sample Supply

Measurement Range

Dimension (width x depth x height)

multi N/C 4300 UV - TOC analyzer (UV digestion)

Focus Radiation NDIR 50 - 20000 µL 1 µg/L Nitrogen 5.0 or Argon 4.6 UV wet chemical digestion Solids TC/TOC/TIC TC, TIC, TOC, DOC, NPOC, NPOCplus 1 - 2 % 3 - 5 min Flow injection 0 - 10000 mg/L 513 mm x 547 mm x 464 mm

For more information about our products and possible variants, please refer to the technical documents or use our contact form.


  • APHA SM 5310 A, B, C, D
  • ASTM D4839
  • DIN EN 13137
  • DIN EN 1484
  • DIN EN 15936
  • EP 2.2.44
  • EPA 415.1
  • EPA 415.3
  • EPA 9060A-1
  • ISO 10694
  • ISO 8245
  • JP 2.59
  • USP 643
  • USP 661.1
  • USP 661.2

Order Information

Order number


450-500.700-2 multi N/C 4300 UV - TOC analyzer (UV digestion)


AS vario Autosampler for flow injection TOC/TNb analyzers 450-900.140
AS vario ER with ext. needle cleaning for multi N/C 3300 and multi N/C 4300 UV 450-900.148
AS 21hp Autosampler for flow injection TOC/TNb analyzers 450-900.106
AS 10e Autosampler for flow injection TOC/TNb analyzers 450-900.111
EPA Sampler with piercing function for flow injection TOC/TNb analyzers 450-126.693
HT 1300 for multi N/C 4300 UV - solids combustion module for TC/TOC analysis 450-126.680
TIC solids module manual 450-126.575


multiWin pro - Operation and data evaluation software for TOC/TNb analyzers

Order number: 450-011.500

The new intuitive software multiWin pro is your user cockpit, with all vital information presented on a single screen. It monitors all key system parameters, clearly presents the measurement results and enables comfortable and targeted operation thanks to its automated, user-friendly workflows. It also offers optional data integrity functions in accordance with FDA 21 CRF Part 11.


The software includes the following features:

  • Sequence table: Live results update, option to measure a single sample using different methods
  • Calibration: Automatic calibration during the measurement sequence with the calibration evaluation applied to subsequent sample measurements
  • Easy Cal: Multi-point calibration from a single standard, including blank correction
  • Reporting: Data evaluation and generation of result reports during an ongoing sequence; user-specific choice of units
  • Conversion functions: Conversion of TOC results into CSB and BSB5 equivalents, TIC values into CO2 levels, and total nitrogen results into total protein contents
  • Self-diagnostics: Automatic and permanent leakage monitoring as well as monitoring of input pressure and internal device pressure, tracking of maintenance intervals, furnace and Peltier temperature, as well as detector status (self-check system)
  • Data export: Automatic or manual in LIMS, CSV and PDF formats
Product Required Included
multi N/C 4300 UV - TOC analyzer (UV digestion) (450-500.700-2)


899-JPPT2SA JP SST kit, UV, JP performance test kit stabilized with H2SO4
899-LIN1SA Linearity test kit, UV, 0.25 mg/L C sucrose for UV digestion TOC systems
899-LIN2SA Linearity test kit, UV, 0.50 mg/L C sucrose for UV digestion TOC systems
899-CLUVSA TOC calibration kit 0.6 mg/L C - UV, sucrose solution stabilized with H2SO4
899-TOCBNS TOC stock solution para-benzoquinone USP, 100 mg/L C
899-TOCSNS TOC stock solution sucrose USP, 100 mg/L C
899-USPS1SA USP TOC SST kit, UV, SST test kit stabilized with H2SO4
402-825.110 Collection tray multi N/C - diameter 100 mm, height 50 mm
450-900.224 Consumables kit for multi N/C4300 UV
402-007.884 FAST connector , straight
402-007.508 FAST connector , straight
402-007.988 FAST connector straight
402-007.513 FAST connector, angled
402-881.027 Finger-Tight-Set 1/16" for tube set, PEEK
402-881.026 Finger-Tight-Set 1/8" for tube set, PEEK
402-810.050 Halogen absorber filling for halogen absorber U-tube, I.D. 11 mm
402-810.083 Halogen absorber filling, 11mm 5 refills of the halogen absorber U-tube, I.D. 11 mm
402-950.012 IC/Condensation vessel for multi N/C 4300 UV
899-00050-0 Low TOC Alpha Sampling Swabs
899-TOCC2A NPOC calibration kit, UV - 0.5 mg/L C, KHP, drinking water calibration
450-900.225 Preventive maintenance kit for multi N/C 4300 UV
402-825.091 Reagent bottle 250 mL for sodium peroxo disulfate
402-825.097 Reagent bottle, 250 ml for phosphoric acid
402-883.005 Sample aspiration tube
402-885.016 Sample aspiration tube with screw joint
402-884.007 Sample purge tube
402-884.026 Sample purge tube with screw joint
899-00049-0 Sample vials 40 mL , clear, TOC<10ppb for EPA sampler
402-825.095 Schott bottle 100 mL with screw cap
402-825.086 Screw cap bottle 2.5 L for ultra-pure rinse water supply
402-950.005 Set of FAST-Connectors , 8 pcs.
402-881.245 Set of TC prefilter and water trap
402-823.033 Syringe 25 mL for syringe pump, 9 port
899-TIC1MNS TIC stock solution 1000 mg/L C Sodium carbonate and sodium hydrogen carbonate 50:50 Mixture
899-W500SA TOC preparation water, UV stabilized with H2SO4 for UV digestion TOC systems
899-TC1MNS TOC stock solution 1000 mg/L C Potassium hydrogenphthalate (KHP)
402-890.305 Tube kit for multi N/C 4300 UV
402-950.001 U-tube halogen absorber O.D. 11 mm
402-815.076 Waste container 5 L


Brochure multi N/C x300 Series (DE)
Brochure multi N/C x300 Series (EN)
Brochure multi N/C x300 Series (KOR)
EU Declaration of Conformity multi NC 4300 UV
Flyer multi N/C Software (DE)
Operating Manual multi N/C 4300 UV (DE)
Operating Manual multi N/C 4300 UV (EN)
Operating Manual multi N/C 4300 UV (ES)
Operating Manual multi N/C 4300 UV (FR)
Operating Manual multi N/C 4300 UV (IT)
Operating Manual multi N/C 4300 UV (JA)
Operating Manual multi N/C 4300 UV (KO)
Operating Manual multi N/C 4300 UV (PL)
Operating Manual multi N/C 4300 UV (RU)
Operating Manual multi N/C 4300 UV (ZH)
Operating Manual multiWin pro (DE)
Operating Manual multiWin pro (EN)
Technical Data multi N/C x300 series (EN)
Technische Daten multi N/C x300 Serie (DE)

Contact us We are happy to help you and will contact you as quickly as possible.